According to studies conducted by the National Highway Traffic Safety Administration (NHTSA) on tire-related crashes, the leading cause of tire failure is underinflation.
Underinflation can have many causes, including a gradual loss of pressure through membranes in the tire itself. It is typical for pressure to drop approximately 1 psi per month and 1 psi for each 8-degree loss in ambient temperature.
Underinflation has immediate effects on vehicle handling (as well as fuel consumption), but its potential impact on overall safety and tire life are even greater. It results in premature and uneven tread wear on the outer edges. Underinflation also increases stress on the carcass itself, through flexing and overheating, which can lead to structural failures such as tread separation.
That's why it is imperative to check and adjust tire pressure at least once a month and before every long trip (over 250 miles). Recommended pressures are printed on a label located on the driver's doorframe or in the glove box.